Obesity and the obesity paradox in patients with severe COVID-19 / Obesidad y paradoja de la obesidad en pacientes con COVID-19 severo: Resultados de dos cohortes prospectivas

Objective: To test the presence of the obesity paradox in two cohorts of patients hospitalized for COVID-19. Design: Two multicenter prospective cohorts. Setting: Three fourth level institutions. Patients: Adults hospitalized in the general ward for confirmed COVID-19 in the three institutions and those admitted to one of the 9 critical care units of one of the institutions. Interventions: None. Main variables of interest: Categorized weight and its relationship with admission to the ICU in hospitalized patients and death in the ICU. Result: Of 402 hospitalized patients, 30.1% were obese. Of these, 36.1% were admitted to the ICU vs. 27.1% of non-obese patients. Of the 302 ICU patients, 46.4% were obese. Of these, mortality was 45.0% vs. 52.5% for non-obese. The requirement to transfer hospitalized patients to the ICU admission get a HR of 1.47 (95%CI 0.87–2.51, p = 0.154) in the multivariate analysis. In intensive care patients, an HR of 0.99 (95%CI: 0.92–1.07, p = 0.806) was obtained to the association of obesity with mortality. Conclusions: The present study does not demonstrate an association between obesity and risk of inpatient transfer to intensive care or death of intensive care patients due to COVID-19 therefore, the presence of an obesity paradox is not confirmed. (AU)

Objetivo: Comprobar la presencia la paradoja de la obesidad en dos cohortes de pacientes hospitalizados por COVID-19. Diseño: Dos cohortes prospectivas multicéntricas. Ámbito: Tres instituciones de cuarto nivel. Pacientes: Adultos hospitalizados en pabellón general por COVID-19 confirmado en las tres instituciones y aquellos internados en alguna de las 9 unidades de cuidado crítico de una de las instituciones. Intervenciones: Ninguna. Variables de interés principales: El peso categorizado y su relación con el ingreso a UCI en hospitalizados y de muerte en UCI. Resultado: Entre 402 hospitalizados 30.1% fueron obesos, de los que 36.1% ingresaron a UCI vs. 27.1% en los no obesos. De los 302 pacientes en UCI, el 46.4% fueron obesos, entre ellos la mortalidad fue de 45.0% vs. 52.5% en los no obesos. En hospitalizados el análisis multivariado obtuvo HR de 1.47 (IC95% 0.87–2.51, p = 0.154) para traslado a UCI. En UCI se obtuvo un OR de 0.99 (IC95%: 0.92–1.07, p = 0.806) para la muerte. Conclusiones: El presente estudio no demuestran una asociación entre la obesidad y el riesgo de traslados a cuidados intensivos en pacientes hospitalizados ni con la muerte en pacientes en cuidados intensivos por COVID-19 por lo que no se confirma la presencia de una paradoja de la obesidad. (AU)

Tecnoestrés y tecnoadicción: el papel de la tecnodependencia en trabajadores de Colombia y México

Introducción: La tecnodependencia es un fenómeno en aumento que podría intensificar riesgos psicosociales como el tecnoestrés y la tecnoadicción, los cuales están asociados al deterioro de la salud y a consecuencias negativas para las organizaciones. Objetivo: Analizar el papel de la tecnodependencia en el tecnoestrés y la tecnoadicción en trabajadores de Colombia y México. Materiales y métodos: Se llevó a cabo un estudio con una estrategia asociativa, predictiva, que contó con 1137 participantes (nacionalidad colombiana = 46 % y nacionalidad mexicana = 54 %). Se utilizó una ficha de datos sociodemográficos y laborales, las escalas de medición de tecnodependencia, tecnoestrés y tecnoadicción. Para el análisis de los datos se realizó un modelo de senderos. Resultados: La generación muda (r = 151), el uso compulsivo del celular (r = 384), el phub-bing (r = 312) y el uso del celular al conducir (r = -0.21) presentaron una relación positiva con el uso excesivo de las tecnologías y una influencia directa en su uso compulsivo. Se concluye que la tecnodependencia cumple un papel predictor del tecnoestrés, y especialmente de la tecnoadicción, en trabajadores colombianos y mexicanos. Es fundamental monitorear el comportamiento de estos riesgos psicosociales emergentes asociados a la tecnología, dadas las implicaciones que tiene en la salud de las personas, sobre todo en el contexto de pandemia.

Introduction: Tech dependence is a growing phenomenon that could intensify psychosocial risks such as technostress and tech addiction, which are associated with health deterioration and negative consequences for organizations. Objective: To analyze the role of tech dependence in technostress and tech addiction in workers in Colombia and Mexico. Materials and methods: A study with an associative, predictive strategy was conducted with 1,137 participants (Colombian nationality = 46% and Mexican nationality = 54 %). A sociodemographic and occupational data sheet was used, as well as scales to measure techno dependence, technostress, and tech addiction. A path model was used for data analysis. Results: Mute generation (r =151), compulsive cell phone use (r =384), phubbing (r=312), and cell phone use while driving (r =-0.21) presented a positive relationship with the excessive use of technologies and have a direct influence on their compulsive use. It is concluded that tech dependence plays a predictive role in technostress, especially tech addiction in Colombian and Mexican workers. Therefore, it is essential to monitor the behavior of these emerging psychosocial risks associated with technology, given the implications on people's health, especially in the context of a pandemic.

Obesity and the obesity paradox in patients with severe COVID-19.

OBJECTIVE: To test the presence of the obesity paradox in two cohorts of patients hospitalized for COVID-19. DESIGN: Two multicenter prospective cohorts. SETTING: Three fourth level institutions. PATIENTS: Adults hospitalized in the general ward for confirmed COVID-19 in the three institutions and those admitted to one of the 9 critical care units of one of the institutions. INTERVENTIONS: None. MAIN VARIABLES OF INTEREST: Categorized weight and its relationship with admission to the ICU in hospitalized patients and death in the ICU. RESULT: Of 402 hospitalized patients, 30.1% were obese. Of these, 36.1% were admitted to the ICU vs. 27.1% of non-obese patients. Of the 302 ICU patients, 46.4% were obese. Of these, mortality was 45.0% vs. 52.5% for non-obese. The requirement to transfer hospitalized patients to the ICU admission get a HR of 1.47 (95%CI 0.87-2.51, p = 0.154) in the multivariate analysis. In intensive care patients, an HR of 0.99 (95%CI: 0.92-1.07, p = 0.806) was obtained to the association of obesity with mortality. CONCLUSIONS: The present study does not demonstrate an association between obesity and risk of inpatient transfer to intensive care or death of intensive care patients due to COVID-19 therefore, the presence of an obesity paradox is not confirmed.

Business support and effects derived from COVID-19: implications on labor productivity.

Introduction: The COVID-19 pandemic shows contagion and mortality rates that exceed the initial forecast and has caused a series of effects in different spheres of individuals, including the labor sphere. Objectives: To examine the relationship between business support and effects derived from COVID-19 in Mexican and Colombian workers and to identify the factors that can predict productivity. Methods: The sample included 482 people from both countries, 381 women (79%) and 101 men (21%). Two instruments were used: one scale to measure business support and the other to measure COVID-19 effects. A multivariate design was used to understand the factorial structure of the instruments through confirmatory factor analysis, and a predictive design was used based on structural equation modeling. Results: Statistical analysis was conducted through the confirmatory factor analysis and found a factorial solution that fitted the theoretical approach to the data in both instruments, and the structural equation model showed an adequate goodness-of-fit (X 2 = 320.110, p = 0.000; comparative fit index = 0.90; root mean square error of approximation = 0.07). Conclusions: According to the results, it was observed that both instruments presented an adequate goodness-of-fit to the data. The structural equation showed that leadership (0,420) and daily disturbance (-0.558) are predictors of labor productivity. Specifically, a positive leadership style facilitated group performance and therefore the achievement of results. Daily disturbance, such as effects derived from COVID-19, negatively affects productivity; therefore, all actions taken by organizations to provide support will promote mental health and will thereby help to achieve the expected productivity.

Early warning scores to identify the risk of clinical worsening or death in patients hospitalized for COVID-19

Background: identifying patients at risk for negative outcomes is key for performing a timely triage and adapting the care intensity for patients with COVID-19. Early warning scores are rules that alert to the risk of adverse outcomes during hospitalization. We sought to validate the modified NEWS, NEWS-2 and COVID-19 Severity Index (CSI). Methods: a prospective observational multicenter study of patients hospitalized for CO VID-19 at three quaternary care hospitals in Bogotá, Colombia, between April and November 2020. The operating characteristics and areas under the ROC curve were calculated. Results: 711 patients were included, in whom the AUC for death was 0.68, 0.58 and 0.68, and for ICU admission was 0.61, 0.63 and 0.66 for mNEWS, NEWS-2 and CSI, respectively. The CSI had the greatest sensitivity for ICU admission or death (87.6 and 90.0%) and NEWS-2 had the greatest specificity (76.8 and 75.5%). Conclusions: the three early warning scores had a low to moderate performance in pre dicting ICU admission or death in patients hospitalized for COVID-19. (Acta Med Colomb 2022; 47. DOI:https://doi.org/10.36104/amc.2022.2225).

Antecedentes: la identificación de los pacientes con riesgo de desenlaces negativos es clave para realizar un triage oportuno y adecuar la intensidad de los cuidados en los pacientes con COVID-19. Las puntuaciones de alerta temprana son reglas para advertir el riesgo de desenlaces adversos durante la hospitalización. Buscamos validar el NEWS modificado, NEWS-2 y COVID-19 Severity Index. Metodología: estudio observacional, prospectivo, multicéntrico con pacientes hospitalizados por COVID-19 en tres hospitales de cuarto nivel en Bogotá (Colombia), entre abril y noviembre de 2020. Se calcularon las características operativas y áreas bajo la curva ROC. Resultados: se contó con 711 pacientes entre los cuales el AUC para muerte fue 0.68, 0.58 y 0.68, y para ingreso a UCI de 0.61, 0.63 y 0.66 para NEWSm, NEWS-2 y CSI respectivamente. El CSI alcanzó la mayor sensibilidad para ingreso a UCI o muerte (87.6 y 90.0%) y la mayor especificidad fue el NEWS-2 (76.8 y 75.5%). Conclusiones: las tres puntuaciones de alerta temprana mostraron un desempeño bajo a moderado para la predicción del ingreso a UCI o muerte en pacientes hospitalizados por COVID-19. (Acta Med Colomb 2022; 47. DOI:https://doi.org/10.36104/amc.2022.2225).

Aceite de Clavo (Eugenol®) como Anestésico en la Especie Panaque Cochliodon-Steindachner, 1879 (Cucha de Ojos Azules) / Clove Oil (Eugenol®) as an Anesthetic in the Species Panaque Cochliodon-Steindachner, 1879 (Blue-Eyed Pleco) / Óleo de Cravo (Eugenol®) como Anestésico na Espécie Panaque Cochliodon-Steindachner, 1879 (Cascudo De Olhos Azuis)

Resumen Introducción: la cucha de ojos azules (Panaquecochliodon) es una especie endémica de la cuenca del Cauca y el Magdalena. Sin embargo, no se tiene mucha información sobre esta especie, incluida la ausencia de un protocolo de sedación adecuado para el trabajo en cautiverio con esta especie. Objetivo: estandarizar un protocolo de sedación del P. cochliodon. Materiales y métodos: se evaluaron diferentes concentraciones del sedante Eugenol que iban desde 20 a 40 mg/L; se adoptaron 4 tipos de sedación y 5 tipos de recuperación, encontrando así los grados de sedación adecuados para los diferentes procedimientos de manejo en confinamiento que se realizaron con esta especie. Resultados: todos los ejemplares alcanzaron la sedación tipo 4 y la recuperación tipo 5 sin mortalidad. Significativamente la concentración a la cual los ejemplares demoraron más tiempo en alcanzar la sedación tipo 4 y recuperación tipo 5 fue la de 20 mg/L, las demás concentraciones no presentaron diferencias entre sí, pero indican una tendencia inversa con respecto a la concentración y el tiempo. Conclusiones: todas las concentraciones evaluadas son seguras para el manejo de P. cochliodon de 314±11,6 gr, no se presentó mortalidad; las concentraciones de 30 a 35 mg/L, ofrecen 2,6 minutos de trabajo, sin efectos deletéreos aparentes sobre la especie.

Abstract Introduction: the blue-eyed pleco {Panaque cochliodon) is a species endemic to the Cauca and Magdalena basin. However, not much information is available on this species, including the absence of an adequate sedation protocol for captive work with this species. Objetive: this research standardizes a sedation protocol for P. cochliodon. Materials and methods: for this purpose, different dosages and concentrations of the sedative Eugenol ranging from 20 to 40 mg/L were evaluated and 4 types of sedation and 5 types of recovery were adopted, thus finding the appropriate degrees of sedation for the different confinement management procedures that were performed with this species. Results: all specimens reached type 4 sedation and type 5 recovery without mortality. Significantly, the concentration at which the specimens took the longest time to achieve type 4 sedation and type 5 recovery was 20 mg / L, the other concentrations did not show differences between them, but indicate an inverse trend with respect to the concentration and experimental time. Conclusions: all the concentrations evaluated are safe for the management of P. cochliodon of 314 ± 11.6 gr, there was no mortality; concentrations of 30 to 35 mg / L, offer 2.6 minutes of work, without apparent deleterious effects on the species.

Resumo Introdução: o cascudo de olhos azuis {Panaquecochliodon) é uma espécie endémica da bacia do Cauca e Magdalena. Contudo, não há muita informação disponível sobre esta espécie, incluindo a ausência de um protocolo de sedação adequado para o trabalho em cativeiro com esta espécie. Objetivo: Esta investigação padronizou um protocolo de sedação para o P. cochliodon. Materiais e métodos: para tanto, foram avaliadas diferentes dosagens e concentrações do sedativo Eugenol variando de 20 a 40 mg/l e adotados 4 tipos de sedação e 5 tipos de recuperação, encontrando-se assim os graus de sedação adequados para os diferentes confinamentos procedimentos de manejo que foram realizados com esta espécie. Resultados: todos os espécimes alcançaram sedação tipo 4 e recuperação tipo 5 sem mortalidade. Significativamente, a concentração na qual as amostras demoraram mais tempo para atingir a sedação do tipo 4 e recuperação do tipo 5 foi de 20 mg/l, as demais concentrações não apresentaram diferenças entre si, mas indicam uma tendência inversa em relação à concentração e ao tempo. Conclusões: todas as concentrações avaliadas são seguras para o manejo de P. cochliodon de 314 ± 11,6 gr, não houve mortalidade; concentrações de 30 a 35 mg/l, oferecem 2,6 minutos de trabalho, sem efeitos deletérios aparentes para a espécie.

Engagementy optimismo en un grupo de trabajadores colombianos: análisis de algunos predictores / Engagement and optimism in a group of Colombian workers: analysis of some predictors

Introducción:El engagementy el optimismo aportan a la salud mental, por tanto, es importante avanzar en la investigación de estos fenómenos psicológicos poco estudiados en Colombia.Objetivo:Analizar la relación entre el engagementy el optimismo en un grupo de trabajadores colombianos, e identificar el papel predictivo de la edad y la antigüedad en la organización en el engagementy el optimismo. Materiales y métodos:Se utilizó una estrategia asociativadondeparticiparon 298 trabajadores (M=124-H=174) de una organización del sector telecomunicaciones. Se aplicó un cuestionario sociodemográfico, el Utrecht Work Engagement Scale-17y el Life Orientation Test. Las hipótesis se probaron mediante correlación de Pearson, análisis de varianza y modelo de regresión lineal múltiple de pasos sucesivos. Resultados:Las dimensiones del engagementse correlacionaron con el optimismo vigor (r=0,42, p<0,01), dedicación (r=0,26, p<0,01) y absorción (r=0,20, p<0,01)). Conjuntamente, se encontraron diferencias en la dedicación en función de la edad (p=0,01) y la antigüedad (p=0,04). Los modelos predictivos reportaron asociaciones entre edad y vigor (ß=0,25, t=4,2, p<0,000), dedicación (ß=0,202, t=3,38, p<0,001) y absorción (ß=0,145, t=2,4, p<0,017).Conclusiones:Existe una relación positiva entre engagementy optimismo. En este estudio la edad es un predictor del engagement, pero no del optimismo.

Introduction:Engagement and optimism contribute to mental health. Therefore, it is important to carry out research on these psychological phenomena that are poorly studied in Colombia. Objective:To analyze the relationship between engagement andoptimism in a group of Colombian workers and identify the role of age and job seniority in predicting these two phenomena. Materials and methods:An associative strategy was applied, with the participation of 298 workers (124 men and 174 women) from a Telecommunications company. The Utrecht Work Engagement Scale-17 and Life Orientation sociodemographic questionnaires were used. The hypothesis was tested through Pearson correlation, variance analysis, and multiple linear regression model with successive steps. Results:The engagement dimensions correlated with optimism (vigor (r=0.42, p<0.01), commitment (r=0.26, p<0.01) and absorption (r=0.20, p<0.01)). Overall, there were differences between commitment in reference to age (p=0.01) and seniority (p=0.04). Predictive models showed associations between age and vigor (ß=0.25, t=4.2, p<0.000), commitment (ß=0.202, t=3.38, p<0.001) and absorption (ß=0.145, t=2.4, p<0.017). Conclusions:There is a positive relationship between engagement and optimism. Based on this study, even though age is a predictor of engagement, it does not play the same role for optimism.

PET/CT F18-FDG with soft tissue plasmacytomas in multiple myeloma.

Multiple myeloma is characterized by malignant proliferation of clonal plasma cells. Usually, appears as a generalized disease but it can present as solitary bone plasmacytoma or a solitary soft tissue mass or extramedullary plasmacytoma. In the case of extramedullary involvement, it could present as soft tissue plasmacytomas and the prognosis is poor. The 18F-FDG PET/CT could be a valuable tool for characterization of the medullary and extramedullary involvement. We present a case of F18-FDG PET/CT with extramedullary involvement with soft tissue plasmacytomas in the setting of MM.

La relación entre la edad, el engagement y la disposición al cambio organizacional / The relationship between age, engagement and disposition to organizational change

Resumen La gestión de recursos humanos como función estratégica en las organizaciones de trabajo constituye en la actualidad una actividad de alta complejidad que implica importantes retos para los líderes de gestión humana a nivel global, debido a los procesos de cambio constante que viven las organizaciones de todo tipo. Estos procesos están dados tanto por exigencias provenientes de las transformaciones del entorno como por los requerimientos internos de ajuste en las organizaciones para mantener su productividad y competitividad en la dinámica de los mercados actuales, condiciones que imprimen serias implicaciones en la gestión del cambio y su relación con el comportamiento, desempeño y compromiso de los trabajadores. El objetivo de esta investigación fue identificar la posible relación entre la edad, el engagement, y la disposición al cambio organizacional, ya que estas variables resultan tener un papel clave en la gestión de recursos humanos en el contexto actual del mundo del trabajo, según se concluye de estudios previos que muestran relaciones entre diferentes tipos de compromiso y procesos de cambio organizacional. La presente investigación se enmarca en la perspectiva de la psicología positiva, un enfoque reciente que busca alejarse del énfasis en lo patológico del comportamiento para centrarse en los aspectos positivos y el potencial del ser humano. Esta perspectiva de la psicología en el campo del estudio del comportamiento organizacional se ha denominado "psicología organizacional positiva". Para lograr los objetivos de identificar la relación entre las variables, se realizó un estudio predictivo, que se orienta fundamentalmente a indagar la relación funcional entre dos o más variables, con un diseño correlacional simple en el que no se utilizan formas de control de variables extrañas que puedan tener influencia en la relación funcional investigada. La muestra estuvo compuesta por 808 personas divididas en dos submuestras (35.5 % colombianos y 65.5 % ecuatorianos), seleccionadas de manera no probabilística accidental. Para la evaluación de las variables se utilizó el autorreporte en la edad, el cuestionario Utrecht Work Engagement Scale (UWES) y el instrumento Disposición al Cambio Organizacional. Los resultados mostraron relaciones significativas entre las variables disposición al cambio organizacional y engagement, tanto a nivel general como en las submuestras. Sin embargo, al indagar sobre el posible papel moderador de la edad entre las otras dos variables, no se encontraron evidencias al respecto. Otros análisis sugieren la posibilidad de un efecto mediado por aspectos culturales que puede incidir en la disposición al cambio. El presente estudio constituye un importante aporte en la comprensión del comportamiento humano en el trabajo en relación con procesos de cambio organizacional, específicamente la asociación de este con variables como el engagement y la edad. Sin embargo, sucesos recientes como la situación mundial derivada de la pandemia por el virus SARSCOV2 y su impacto en las dinámicas de trabajo sugieren la necesidad de avanzar en estudios complementarios al realizado por los autores y que se presenta en este artículo, puesto que las actividades laborales han migrado para muchas personas del contexto de la empresa al contexto del hogar, lo que pone en escena otras variables que podrían incidir en la relación aquí indagada.

Abstract Human resource management as a strategic function in work organizations is currently a highly complex activity that implies significant challenges for human management leaders at a global level, due to the processes of constant change that all kind of organizations must experience, due to demands arising from the transformations of the environment and the internal requirements of adjustment in organizations to maintain their productivity and competitiveness in the dynamics of current markets, conditions that have serious implications in the management of change and its relationship with behavior , performance and commitment of the workers.. In this context, the human resources area has the important task of contributing to the management of human talent to achieve high levels of commitment from people in organizations and facilitate change processes, if organizational leaders want to achieve strategic objectives in a much more effective way. To achieve this, it is necessary to identify key variables that affect human behavior in work contexts and understand the possible relationships between these variables. The main objective of this research was to identify the relationship between age, engagement, and disposition to organizational change since these variables turn out to have a key role in human resource management in the current context of the world of work. The present investigation is framed in the perspective of positive psychology, a recent approach that seeks to move away from the emphasis on the pathological behavior to focus on the positive aspects and potential of the human being. This is the perspective of psychology in the field of the study of organizational behavior has been called positive organizational psychology. To achieve the objectives of identifying the relationship between the variables, a predictive study with a simple correlational design was performed. This kind of study is mainly oriented to investigate the functional relationship between two or more variables in which no forms of control of strange variables are used. The sample was made up of 808 people divided into two sub-samples (35.5 % Colombian and 65.5 % Ecuadorian), selected in an accidental non-probabilistic way; The self-report on age, the Utrecht Work Engagement Scale (UWES) questionnaire and the instrument Disposition to organizational change were used to evaluate the variables. The results showed significant relationships between the variables disposition to organizational change and engagement, both in general and in the subsamples; however, when investigating the possible role of age in moderating the other two variables, no evidence was found in this regard. Other analyzes suggest the possibility of an effect mediated by cultural aspects that may affect the readiness to change. However, recent events such as the world situation derived from the SARSCOV2 virus pandemic and its impact on work dynamics, suggest the need to advance in complementary studies to the one carried out by the authors and presented in this article, since the Work activities have migrated for many people from the context of the company to the context of the home, which highlights other variables that could affect the relationship investigated here.

68Ga-DOTANOC PET/CT With Lung Involvement in the Era of COVID-19 Pandemic.

ABSTRACT: Patient was a 55-year-old man with history of pancreas neuroendocrine tumor grade 2, Ki-67 index 10%. He was treated with surgical resection. 68Ga-DOTANOC PET/CT was performed as part of follow-up of known disease. The images showed opacities in both lungs' parenchyma with moderate uptake of radiotracer and mediastinal lymph nodes with high uptake suggestive of infection. Two weeks before a high-resolution CT was performed, these findings in the lungs were not present. The patient was asymptomatic and was referred to the emergency department for reverse transcriptase-polymerase chain reaction COVID-19 test, and the result was positive.

Incidental findings of COVID-19 in F18-FDG PET/CT from asymptomatic patients with cancer in two healthcare institutions in Bogotá, Colombia / [Hallazgos incidentales de COVID-19 en tomografías PET/CT 18F-FDG de pacientes asintomáticos con cáncer en dos instituciones de salud de Bogotá, Colombia].

COVID-19 is the viral infection caused by SARS-CoV-2 declared by the World Health Organization (WHO) as a pandemic. Patients with cancer have a higher risk to acquire the infection and worse prognosis as they have to attend more medical visits in healthcare institutions, receive medical and surgical treatments, and be subjected to diagnostic studies such as PET/CT in nuclear medicine services where the infection may be an incidental finding. We present here F18-FDG PET/CT (Positron Emission Tomography and Computed Tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose), images with findings of COVID-19 from patients with different oncological conditions but no respiratory symptoms.

La COVID-19 es la infección viral causada por el SARS-CoV-2 y declarada por la Organización Mundial de la Salud (OMS) como pandemia. Los pacientes con cáncer tienen un mayor riesgo de adquirir la infección y un peor pronóstico, ya que deben asistir a visitas médicas en diferentes centros hospitalarios, reciben tratamientos médicos y quirúrgicos y deben someterse a estudios diagnósticos como la PET/CT en servicios de medicina nuclear, lo que es ocasión para el hallazgo incidental de la infección. Se presentan las imágenes de tomografías computarizadas por emisión de positrones con 18-fluorodesoxiglucosa (F18) (Positron Emission Tomography and Computed Tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose, PET/CT F18-FDG) en las que se evidenció la COVID-19 en pacientes con diversas enfermedades oncológicas, pero sin sintomatología respiratoria.

68Ga-PSMA PET/CT With Incidental Finding of COVID-19 in an Asymptomatic Patient.

A 70-year-old man with prostate adenocarcinoma was diagnosed by transrectal biopsy, with Gleason of 4 + 5 and initial PSA of 225 ng/mL since March 2020. Ga-PSMA PET/CT was performed as part of initial staging. The images showed an enlarged prostate with focal PSMA uptake in both lobes. Retroperitoneal and pelvic lymph nodes with moderate uptake of PSMA were shown. Another finding was a moderate PSMA uptake in the both lung parenchymas associated with opacities in CT. The patient denied any symptoms of coronavirus disease and was referred to the emergency department for RT-PCR COVID-19, and the result was positive.

Hallazgos incidentales de COVID-19 en PET/CT 18F-FDG de pacientes asintomáticos con cáncer en dos instituciones de salud de Bogotá, Colombia / Incidental findings of COVID-19 in F18-FDG PET/CT from asymptomatic patients with cancer in two healthcare institutions in Bogotá, Colombia

La COVID-19 es la infección viral causada por el SARS-CoV-2 y declarada por la Organización Mundial de la Salud (OMS) como pandemia. Los pacientes con cáncer tienen un mayor riesgo de adquirir la infección y un peor pronóstico, ya que deben asistir a visitas médicas en diferentes centros hospitalarios, reciben tratamientos médicos y quirúrgicos y deben someterse a estudios diagnósticos como la PET/CT en servicios de medicina nuclear, lo que es ocasión para el hallazgo incidental de la infección. Se presentan las imágenes de tomografías computarizadas por emisión de positrones con 18-fluorodesoxiglucosa (F18) (Positron Emission Tomography and Computed Tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose, PET/CT F18-FDG) en las que se evidenció la COVID-19 en pacientes con diversas enfermedades oncológicas, pero sin sintomatología respiratoria.

COVID-19 is the viral infection caused by SARS-CoV-2 declared by the World Health Organization (WHO) as a pandemic. Patients with cancer have a higher risk to acquire the infection and worse prognosis as they have to attend more medical visits in healthcare institutions, receive medical and surgical treatments, and be subjected to diagnostic studies such as PET/CT in nuclear medicine services where the infection may be an incidental finding. We present here F18-FDG PET/CT (Positron Emission Tomography and Computed Tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose), images with findings of COVID-19 from patients with different oncological conditions but no respiratory symptoms.

Bronchoscopic Lung Volume Reduction with Valves and Coils. A Network Meta-analysis.

Background: Coils and endobronchial valves are the most widely used bronchoscopic lung volume reduction devices in patients with advanced emphysema. However, the choice of each specific device depends on emphysema characteristics (homogeneous vs. heterogeneous) and presence of lobar collateral ventilation (CV). These devices have not been compared in a head-to-head study design.Objectives: To conduct a network comparative meta-analysis studying the effect of valves in patients with heterogeneous emphysema without CV, and to also study the effects of valves and coils in patients with mixed homogeneous and heterogeneous emphysema.Data Sources and Data Extraction: PubMed and Web of Science were searched for potentially includable randomized active comparator trials from inception to January 20, 2020, and data were extracted in the working sheets of Comprehensive Meta-analysis.Synthesis: Network meta-analysis was conducted in R program using package "netmeta."Results: In patients with heterogeneous emphysema without CV, both Spiration and Zephyr valves showed significant increases in forced expiratory volume in 1 second (FEV1) (0.11 L [95% confidence interval (CI), 0.05 to 0.16] and 0.14 L [0.08 to 0.19], respectively) and in reducing St. Georges Respiratory Questionnaire (SGRQ) scores (-9.32 [-14.18 to -4.45] and -8.14 [-11.94 to -4.35], respectively) as compared with control, with no significant interintervention differences. Only Zephyr valves showed significant improvement (52.3 m [95% CI, 26.53 to 77.93]) in six-minute walk distance (6MWD). Both were ranked as equally efficacious in these patients. In the mixed homogeneous and heterogeneous emphysema group of patients, both Zephyr valves and coils showed significant increases in FEV1 and 6MWD and reduction in SGRQ, as compared with control. Although there were no significant interintervention differences, the magnitude of improvement in these parameters was highest with Zephyr valves (e.g., 6MWD increased by 56.74 m [23.66 to 89.81] vs. 30.31 m [4.00 to 56.63]) in coils), ranking them first. In both populations, these interventions showed a statistically significant association with procedure-related pneumothorax but not with chronic obstructive pulmonary disease exacerbation.Conclusions: In patients with heterogeneous emphysema without CV, both Zephyr and Spiration valves were equally efficacious in FEV1 and SGRQ improvement. However, in the mixed patients with homogeneous and heterogeneous emphysema, Zephyr valves show relative superiority over coils especially with respect to improvement in 6MWD.

Aspectos de la cultura organizacional y su relación con la disposición al cambio organizacional / Aspects of organizational culture and its relation to the organizational change disposition

Resumen El objetivo de esta investigación fue determinar la relación entre la cultura organizacional y la disposición al cambio organizacional. Se trata de una investigación empírica que, de acuerdo con el objetivo de investigación, responde a una estrategia asociativa, en un estudio predictivo desarrollado bajo un diseño correlacional simple. La muestra estuvo compuesta por 558 participantes de cuatro entidades de educación superior. Para la evaluación de las variables se emplearon la adaptación para Colombia del OCAI (Organizational Culture Assessment Instrument) y la prueba Disposición al Cambio Organizacional. Los resultados mostraron relaciones significativas entre los factores y los tipos de cultura organizacional con las macro y microdimensiones de la disposición al cambio organizacional. También se encontraron diferencias significativas entre las instituciones en las dimensiones grupal y organizacional de la disposición al cambio, en el factor organizacional y en el tipo de cultura jerárquica. Se evidencia cómo la cultura organizacional se relaciona particularmente con aspectos organizacionales y la comunicación empresarial.

Abstract The objective of this research was to determine the relationship between aspects of organizational culture and the disposition to organizational change. A quantitative, nonexperimental study was carried out under a comparative design; with a sample of 558 participants from four higher education institutions. The instruments used allowed the evaluation of the organizational culture -OCAI- and the willingness to change. The results showed significant relationships between the factors and the types of organizational culture with the macro and micro dimensions of the disposition to organizational change. Significant differences were also found between the institutions in the group and organizational dimensions of the disposition to change; in the organizational factor and the type of hierarchical culture. It is evident how the organizational culture is particularly related to organizational aspects and business communication.

Diversidad del perifiton presente en un sistema de producción de tilapia en biofloc

Introducción. El perifiton está formado por una compleja comunidad de organismos acuáticos que se adhieren a los sustratos bajo el agua, se constituye en componente fundamental de las comunidades bióticas acuáticas y permite comprender el funcionamiento de estos ecosistemas. Algunas variaciones en la calidad del biofloc en cuanto a proteína cruda y a niveles de ácidos grasos poliinsaturados pueden ser condicionadas principalmente por la estructura del perifiton. Objetivo. Determinar la composición, abundancia e índices de diversidad del perifiton presente en los diferentes tratamientos para el cultivo de tilapia en biofloc. Materiales y métodos. Se tomaron cinco muestras de un cultivo de tilapia en biofloc asociado a tres tratamientos con su respectivo control en un periodo de seis meses. Se empleó un microscopio invertido con cámara integrada para el montaje y conteo de la muestra (cámara de Sedgwick-Rafter). Para la determinación y composición del ensamble se emplearon claves taxonómicas y se estimaron los índices de diversidad, dominancia, riqueza y equidad de especies. Para el cálculo del índice de diversidad y el esquema de agrupamiento, se emplearon los programas Biodiversity-Professional (Versión 2) y PAST (Versión 2.17c). Resultados. El ensamble estuvo compuesto por 15 taxones. La clase Eurotatoria fue la de mayor representatividad con respecto a la riqueza de taxones. La especie más abundante fue Crucigenia fenestrata. Los muestreos realizados en distintos meses del año arrojaron diferencias en cuanto a la densidad poblacional y el número de taxones encontrados. Los índices de diversidad oscilaron entre 0,3428 bel nat/ind y 0,7357 bel nat/ind. Para la equidad se encontraron valores cercanos o mayores a 1 y menores a 0,8 como el tratamiento 2 y la riqueza de taxones mostró regularidad entre los tratamientos. Conclusión. Las microalgas perifíticas representan una de las comunidades con mayor variabilidad espacial en términos de biomasa y composición, pero ninguna de la especies mantiene a lo largo del año un tamaño considerable de su población, en parte debido a que las perturbaciones en los tratamientos modifican su estructura

Introduction. Periphyton is comprised of a complex community of aquatic organisms that get attached to underwater substrates, is a crucial component of the aquatic biotic communities and contributes to the understanding of these ecosystems. Some variations in the biofloc´s quality in raw protein and polyunsaturatted fatty acids levels terms can be conditioned mainly by periphyton´s structure. Objective. Determine the composition, abundance and diversity rates of periphyton in the different treatments for cultivating tilapia fish in biofloc. Materials and methods. Five samples of a tilapia fish culture in biofloc, associated to three treatments with their respective controls during a six months period, were taken. An inverted microscope with a camera was used to mount and count the sample (Sedgwick-Rafter camera). To determine and compose the assembly, taxonomic keys were used, and the species´ diversity, dominance, richness and equity rates were estimated. To calculate the diversity rate and the grouping scheme, the Biodiversity-Professional (Version 2) and PAST (Version 2.17c) softwares were used. Results. The assembly was comprised of 15 taxa. Eurotatoria was the most representative in taxa richness terms. The most abundant species was Crucigenia fenestrata. The sampling developed in different months of the year showed differences concerning the population density and the number of taxa found. The diversity rates oscilated between 0,3428 bel nat/ind and 0,7357 bel nat/ind. For the equity, values close or above 1 were found, and values under 0, 8 were also found as treatment 2 and the taxa richness showed a regularity between treatments. Conclusion. Periphytic microalgae represent one of the communities with the highest space variability in terms of biomass and composition, but none of the species maintain a considerable size of its population throughout the year, partly because of the disturbances in the treatments, which make them change their structure

Introdução. O perifiton está formado por uma complexa comunidade de organismos aquáticos que se aderem aos substratos sob a água, se constitui em componente fundamental das comunidades bióticas aquáticas e permite compreender o funcionamento destes ecossistemas. Algumas variações na qualidade do biofloc em quanto a proteína crua e a níveis de ácidos grassos poli-insaturados podem ser condicionadas principalmente pela estrutura do perifiton. Objetivo. Determinar a composição, abundância e índices de diversidade do perifiton presente nos diferentes tratamentos para o cultivo de tilápia em biofloc. Materiais e Métodos. Se tomaram cinco amostras de um cultivo de tilápia em biofloc associado a três tratamentos com seu respectivo controle num período de seis meses. Se empregou um microscópio invertido com câmera integrada para a montagem e contagem da amostra (câmera de Sedgwick-Rafter). Para a determinação e composição da montagem se empregaram chaves taxonômicas e se estimaram os índices de diversidade, dominância, riqueza e equidade de espécies. Para o cálculo do índice de diversidade e o esquema de agrupamento, se empregaram os programas Biodiversity-Professional (Versão 2) e PAST (Versão 2.17c). Resultados. A montagem esteve composta por 15 táxones. A classe Eurotatoria foi a de maior representatividade com respeito à riqueza de táxones. A espécie mais abundante foi Crucigenia fenestrata. As amostras realizadas em distintos meses do ano mostraram diferenças em quanto à densidade populacional e o número de táxones encontrados. Os índices de diversidade oscilaram entre 0,3428 bel nat/ind e 0,7357 bel nat/ind. Para a equidade se encontraram valores próximos ou maiores a 1 e menores a 0,8 como o tratamento 2 e a riqueza de táxones mostrou regularidade entre os tratamentos. Conclusão. As microalgas perifíticas representam uma das comunidades com maior variabilidade espacial em termos de biomassa e composição, mas nenhuma da espécies mantém ao longo do ano um tamanho considerável de sua população, em parte devido a que as perturbações nos tratamentos modificam sua estrutura

Actividad física y comportamientos sedentarios de escolares de Córdoba en su tiempo libre y en clase de educación física / Physical activity and sedentary behaviors during leisure time and physical education class in school children in Córdoba

INTRODUCCIÓN: en todo el mundo se recomienda que niños y niñas acumulen al menos 60 minutos diarios de actividad física (AF) y reduzcan el comportamiento sedentario a unmáximo de dos horas diarias, con el fin de promover el bienestar y prevenir enfermedades. OBJETIVOS: Describir la frecuencia de AF y actividades sedentarias (AS) en horario escolar y extraescolar, según género y nivel socioeconómico (NSE). MÉTODOS: Se realizó un estudio transversal en una muestra aleatoria de 1577 niños/asde 19 escuelas primarias municipales de Córdoba en 2011. Se usó una encuesta autoadministrada para indagar frecuencia y duración de AF y AS extraescolares y una escala para evaluar NSE familiar. Se utilizó el SOFIT (System for Observing Fitness Instruction Time) para evaluar AF y AS durante la clase de Educación Física (EF). RESULTADOS: El 64% cumplía con la recomendación diaria de AF. Se observaron diferencias por género y NSE familiar en la AF. Durante la semana, el 44 y el 46% ocupaban más de dos horas diarias con televisión y computadora, respectivamente (porcentaje mayor en varones). La duración promedio de las clases de EFera menor a 40 minutos, y el 57% del tiempo se realizaban AS. CONCLUSIONES: Pese a que la mayoría de los escolares declaran ser físicamente activos en su tiempo libre, esto depende del NSE familiar y del género. Las clases de EF presentan escasa AF y elevada AS, lo que implica desaprovechar ese espacio comodispositivo clave en la promoción de estilos de vida activos.

INTRODUCTION: it is globally recommended that children get at least 60 minutes of physical activity (PA) and reduce sedentary behavior to a maximum of two hours a day in order topromote wellness and prevent diseases. OBJECTIVES: To describe thefrequency of PA and sedentary activities (SA) inside and outside ofschool hours, according to gender and socioeconomic status (SES). METHODS: A cross-sectional study was performed with a random sample of 1577 children of 19 municipal elementary schools inthe city of Cordoba in 2011. A self-administered questionnaire wasused to investigate the frequency and duration of extracurricular PA and SA, with a scale to measure family SES. The SOFIT (System for Observing Fitness Instruction Time) tool was used to assess PA and SA during physical education class. RESULTS: A total of64% met the daily recommendation of PA. There were found to be differences according to gender and family SES. During each week, 44 and 46% of the students spent more than two hours aday watching TV and on their computer, respectively (with a higherpercentage of boys). The average duration of physical education classes was less than 40 minutes, and SA were performed during 57% of the class time. CONCLUSIONS: Although most students report being physically active in their free time, this depends ongender and family SES. Physical education classes contribute poorly to PA and highly to SA, wasting opportunities provided by the school space as a key device for promoting active lifestyles.

Las publicaciones periódicas en el marco de la enseñanza de la psicología en la Universidad Nacional de La Plata (Argentina): 1976- 2000 / Graduate Psychology Education in National University of La Plata (Argentina) and the Role of Scientific Journals, 1976-2000

Desde una perspectiva que reúne una historia de la enseñanza de la psicología y una historia institucional de las publicaciones periódicas (revistas), se analiza la enseñanza de la psicología en la Universidad Nacional de La Plata en el período 1976-2000. Se hace una primera descripción de la misma, a partir del estudio sociobibliométrico de las referencias bibliográficas de los programas de los cursos enseñados en dicho período en la carrera. Se focaliza en la incidencia de las publicaciones periódicas referenciadas en dichos cursos, analizándolas cuantitativa y cualitativamente, desde un enfoque sociobibliométrico.

This work is at the intersection of two lines of historical research: a psychology education history and a scientific journal history. It is attemped to analyze the teaching of Psychology at the National University of La Plata (UNLP), during the period 1976-2000. A first description of it is outlined by making use of a socio-bibliometrical analysis of the references at the syllabus of the courses taught at the Program of Psychology at the UNLP in such a period. The incidence of the journals referenced at the syllabus is quantitatively and qualitatively analyzed to highlight their incidence in the contents taught.

El museo como espacio de formación: el caso de la psicología en San Luis (Argentina) / The museum as a space for training. The case of the Psychology in san luis (argentina)

Se propone el museo como espacio educativo y se discute su rol en la enseñanza disciplinar en la educación superior. Se presenta una experiencia educativa en torno al Museo de Historia de la Psicología de la Facultad de Psicología de la Universidad Nacional de San Luis (Argentina), y su aporte a la formación de competencias generales y específicas de los futuros psicólogos. Se asume con los estudiantes el rol político de una historia cultural disciplinar que cuestiona la configuración de modelos científicos profesionales. Se realiza una propuesta de investigación de objetos culturales que representan diversas tradiciones disciplinares. Desde la consigna de descubrir objetos históricos en contexto, investigarlos, ponerlos en valor y comunicar los resultados. Se interpela el pasado disciplinar: sus certezas, ortodoxias y hegemonías socialmente construidas, y se configura un espacio de formación de competencias científico-profesionales. Asimismo, se propone la participación en el Museo como espacio de comunicación pública de la ciencia, para la incidencia en la cultura más amplia del público no especializado

It is proposed the museum as educational space and discuss its role in the teaching discipline in higher education. It presents an educational experience around the Museum of the Psychology's History of the Faculty of Psychology at the National University of Saint Luis (Argentina), and its contribution to the training of general and specific competences of future psychologists. It is assumed with the students the political role of a cultural history of this discipline that questions the configuration of scientific professional models. It is made a research propose of cultural objects that represent different discipline traditions. From the slogan to discover historical objects in context, to research them, to put them in value and to communicate results. It is questioned the past discipline: its certainties, orthodoxies and socially constructed hegemonies, and sets up a space of training competences scientific-professionals. It is also proposed that the participation in the museum as a space for public communication of science, to the incidence in the wider culture of the non-specialist audience.